Sr. Scientist I (Immunology) - in vitro & in vivo studies

ModeX Therapeutics is seeking a highly skilled and motivated Senior Scientist with experience in immunology to support the development and progression of new immune therapies.  The successful candidate will work with ModeX’s team to test novel biologic drug candidates, delineate their mechanism of action, and address biological questions. This is an exciting opportunity to be part of a cross-functional team and contribute to the development of next-generation therapeutics in a fast-paced, rapidly growing biotech company with a bold vision. 

Key Responsibilities:

• Play a key role in the development of new biologic drugs for immunotherapy
• Independently propose, plan and perform in vitro and in vivo studies to characterize the company’s drug candidates and their mechanism of action
• Establish mechanistic insights addressing the impact of novel targets on immune responses
• Develop and perform complex functional assays using primary immune cells (human, mouse, NHP)
• Design, develop, troubleshoot and establish in vitro assays and in vivo models and standard operating procedures as needed
• Collaborate cross-functionally with project teams to ensure data-driven decision-making and timely progression of programs.
• Contribute to scientific communications, including internal reports and presentations

Qualifications:

• B.S. or M.S. in immunology, immune-oncology or related field
• Sr. Scientist I: 15+ years of relevant research experience; must have industry experience (10+ years)
• Strong, hands-on expertise in immunology and immunotherapy, with the ability to independently evaluate and apply new concepts and immunoassays
• Demonstrate mastery of complex functional assays using primary immune cells, including multi-color flow cytometry, ELISA and Luminex
• Extensive experience with in vivo studies, incl. including mouse handling, multiple dosing routes (IV, IP, SC), tumor models, and tissue collection
• Proven ability to work independently, prioritize effectively, and drive projects forward in a fast-paced biotech environment
• Excellent written and oral communication, organization, and data analysis skills
• Outstanding troubleshooting and problem-solving skills
• Highly collaborative mindset, with the confidence to contribute new ideas and mentor junior team members as needed

ModeX Therapeutics is an Equal Opportunity Employer

ModeX Therapeutics, an OPKO Health company, is the leading clinical-stage biopharmaceutical company developing unique and proprietary-multispecific therapeutics. Its MSTAR platform unites the power of multiple biologics in a single molecule to create multispecific antibodies that bind four or more targets with unprecedented versatility and potency for complex diseases. Its promising first-in-class immunology pipeline includes candidates against immune diseases, including cancer (both solid and hematologic tumors), immune impairment, as well as several of the world's most pressing viral threats. Its founding team includes globally recognized medical innovators with proven track records of delivering breakthroughs for patients. ModeX is based in Weston, Massachusetts. For more information, please visit www.modextx.com.