Senior Scientist

We are seeking an experienced Senior Scientist in In Vivo Pharmacology & Translational Research to join a fast-paced, high-growth biotechnology company. In this pivotal role, you will design, coordinate, and oversee preclinical in vivo studies through external CRO partners, playing a central role in establishing robust proof of concept across innovative oncology pipelines.

Key Responsibilities

• In Vivo Study Design & Execution: Independently design and plan robust preclinical in vivo studies (including efficacy, PK/PD, target engagement, mechanism of action, and tolerability) utilizing appropriate oncology models (CDX, PDX, and others). Ensure full compliance with relevant animal license and ethical standards.
• CRO Management & Oversight: Lead the scientific coordination and oversight of outsourced in vivo studies, including CRO selection, protocol development, study execution, troubleshooting, and rigorous quality control to ensure delivery of high-quality data on schedule.
• Data Analysis & Strategic Interpretation: Analyze and integrate complex in vivo efficacy, PK/PD, and pharmacodynamic biomarker data to evaluate compound performance, guide candidate optimization, and drive go/no-go decisions for pipeline progression.
• Translational Pharmacology: Develop and implement translationally relevant i...