Associate Principal Scientist – Biology

Associate Principal Scientist – Biology
Location: UK | Hybrid

Pharmaron is seeking an experienced Associate Principal Scientist – Biology to lead biological strategy across integrated small molecule drug discovery projects. This is a critical, client-facing role supporting programmes from hit identification through to candidate selection, working across multiple therapeutic areas and modalities.

The Integrated Drug Discovery (IDD) Services group at Pharmaron is responsible for leading and delivering drug discovery projects for our client partners. The team comprises scientific expertise and strategic leadership across medicinal chemistry, CADD, biology, DMPK and translational science. Combined with Pharmaron’s global research capabilities we design and deliver integrated programmes from target identification and hit finding through to IND filing.

Working closely with our partners we define strategy, coordinate execution across teams and with an AI enabled accelerated Design–Make–Test–Analyse cycles support the progression of projects and innovative medicines towards the clinic.

The Role

• Lead and deliver biology strategy across discovery programmes, from hit-finding to candidate selection
• Provide scientific and technical leadership to develop assays to address key project questions, such as mechanism of action and biological differentiation
• Interpret in vitro data and guide data-driven decision making to advance projects
• Collaborate closely with global teams and partner organisations to ensure efficient project delivery
• Apply innovative problem-solving to overcome technical challenges
• Present data, strategy and progress to internal stakeholders and external partners
• Support proposal development and new business opportunities
• Maintain compliance with GxP, SOPs and regulatory standards

About You

PhD in Pharmacology, Biological Sciences or related discipline
5–10+ years’ experience in a drug discovery biology role (Pharma, Biotech or CRO)
Strong track record supporting small molecule drug discovery programmes
Experience managing external collaborations and cross‑functional teams

Key Skills

• Deep expertise in in vitro biology assays and data interpretation
• Strong understanding of drug discovery processes, including DMPK and toxicology considerations
• Proficiency in data analysis and relevant scientific software
• Ability to translate complex data into clear scientific direction

Key Attributes

• Proactive, accountable and delivery‑focused
• Strong decision‑making and scientific judgement
• Collaborative and effective across global, matrixed teams
• Adaptable, organised and comfortable managing multiple priorities
• Passion for innovation and continuous learning

Why Join Pharmaron?

Work on diverse, cutting‑edge discovery programmes
Collaborate with global scientific experts
Play a key role in delivering innovative therapies
Be part of a growing, client‑focused CRO environment