Clinical Bioinformatician

Job summaryWe are seeking a skilled and enthusiastic Clinical Bioinformatician to join our team based in the North Thames Genomic Laboratory Hub at Great Ormond Street Hospital. Our team is delivering transformation in patient care by developing pipelines for rapid, comprehensive diagnosis of rare diseases. If you are committed to contributing to a team delivering excellence in rare disease bioinformatics this is definitely the post for you.You will be joining an enthusiastic, friendly, motivated Clinical Bioinformatics Team. This is an ideal opportunity to seriously contribute to clinical practice for the benefit of patients. This post is suitable for registered Clinical Bioinformaticians or Trainee Bioinformaticians close to registration. The role includes a minimum requirement of 20% onsite working, although the expectation is that you will work onsite for 40% of the week to support service delivery, collaboration and team integration.Main duties of the jobYou will be working within a team of Bioinformaticians supporting diagnostics services at Great Ormond Street Hospital. The role will be a mix of acting as Duty Bioinformatician, development work and data analysis to support the rare disease diagnostic service. The Duty Bioinformatician ensures the smooth operational delivery of the service and answers daily issues raised by the scientific teams. Development work includes working on new and updating existing pipelines and database projects, as well as evaluations of applications and infrastructure planning. Supporting scientific and clinical teams is also an important part of the role, requiring strong data analysis and presentation skills.It is likely that the majority of the role will be supporting the development of the service, but individuals will need to cover all aspects of the role. Having a broad set of programming skills and IT knowledge will be required. You will be responsible for ensuring that all work is completed to a high standard within defined timelines. You will be expected to work efficiently as part of the Bioinformatics Team and as a supportive team member.Compliance with UKAS ISO15189 standards is required, along with ensuring that the bioinformatics quality standards are maintained.About usWe are keen to make our workforce as diverse asthe communities we serve, and we hope to attract applications from underrepresented groups, includingpeople withBlack, Asian and Minority Ethnicheritage, people with a disability, and peoplefrom LGBTQ+ communities.By growing an ever more diverse workforce, we'll have a greater range of perspectives and knowledge, meaning that we can provide the children andyoung people at our hospital with even better care.Our hospital is committed to creating an environmentthat is open and inclusive. Our staff are encouragedto engage with colleagues through the following networks: REACH (Race, Ethnicity and Cultural Heritage) ENABLED (Enhancing Abilities & Leveraging Disabilities Network), PRIDEandWomen's networks; all of which are sponsored by a member of our Executive Management Team.We want to ensure that all of our people, regardless of their background, are seen and heard. We want to attract applicants that share our commitment to inclusion and that understand diversity is a strength that is embraced and valued.formed around interests, issues and a common bond or background. Staff network members create a positive and inclusive work environment at Great Ormond Street Hospital by actively contributing to the Trust's mission, values and efforts specific to inclusion. All of our staff networks are open to any employee.DetailsDate posted09 September 2026Pay schemeAgenda for changeBandBand 7Salary 58,133 to 65,261 a year Inclusive per annum ContractPermanentWorking pattern Full-time Reference number271-GEN-8204714Job locationsGreat Ormond Street Hospital for Children NHS Foundation TrustGreat Ormond Street HospitalLondonWC1N 3JHUnited KingdomJob descriptionJob responsibilitiesThe full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience, and knowledge required. For both documents please view the attachment. Job description Job responsibilitiesThe full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience, and knowledge required. For both documents please view the attachment.Person Specification GOSH Culture and Values EssentialOur Always valuesAble to work on site when required Academic/Professional qualification/Training EssentialState Registered Clinical Bioinformatician (HCPC)MSc in Bioinformatics/Computational Biology or equivalent Postgraduate qualificationDesirableHigher degree (PhD) in Bioinformatics or a related field Experience/Knowledge EssentialAdvanced knowledge of the Python programming language, and commonly used Python libraries and web frameworks (e.g. Django and Flask)Knowledge of confidentiality and data protection processes and proceduresExperience of developing, implementing and maintaining bioinformatic data analysis pipelinesExperience with creating, querying and maintaining databases, particularly MySQL or PostgreSQLAdvanced use of git version controlDemonstrable experience in a clinical diagnostic departmentKnowledge of bash and shell scriptingAbility to work in a Unix/Linux environmentUp to date knowledge of the relevant scientific literatureEvidence of professional and personal development.Experience in scientific workflow languages for genomic pipelines (e.g. Nextflow)DesirableExperience using docker for developmentExperience deploying software in the cloud Skills/Abilities EssentialExcellent organisational and time management skills with ability to prioritise tasks effectivelyAbility to develop and maintain excellent communication and working relationshipsAble to provide specialist advice to laboratory staffAble to present data at departmental and inter-departmental meetingsAwareness of clinical significance of genetics findings and implications for patientsWork to deadlines, operating autonomously and as part of a teamKnowledge and understanding of ISO15189 accreditation standards and their application to a genomics laboratoryAbility to write and follow bioinformatics protocols Person Specification GOSH Culture and Values EssentialOur Always valuesAble to work on site when required Academic/Professional qualification/Training EssentialState Registered Clinical Bioinformatician (HCPC)MSc in Bioinformatics/Computational Biology or equivalent Postgraduate qualificationDesirableHigher degree (PhD) in Bioinformatics or a related field Experience/Knowledge EssentialAdvanced knowledge of the Python programming language, and commonly used Python libraries and web frameworks (e.g. Django and Flask)Knowledge of confidentiality and data protection processes and proceduresExperience of developing, implementing and maintaining bioinformatic data analysis pipelinesExperience with creating, querying and maintaining databases, particularly MySQL or PostgreSQLAdvanced use of git version controlDemonstrable experience in a clinical diagnostic departmentKnowledge of bash and shell scriptingAbility to work in a Unix/Linux environmentUp to date knowledge of the relevant scientific literatureEvidence of professional and personal development.Experience in scientific workflow languages for genomic pipelines (e.g. Nextflow)DesirableExperience using docker for developmentExperience deploying software in the cloud Skills/Abilities EssentialExcellent organisational and time management skills with ability to prioritise tasks effectivelyAbility to develop and maintain excellent communication and working relationshipsAble to provide specialist advice to laboratory staffAble to present data at departmental and inter-departmental meetingsAwareness of clinical significance of genetics findings and implications for patientsWork to deadlines, operating autonomously and as part of a teamKnowledge and understanding of ISO15189 accreditation standards and their application to a genomics laboratoryAbility to write and follow bioinformatics protocolsDisclosure and Barring Service CheckThis post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.Certificate of SponsorshipApplications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).UK Registration Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window). Additional information Disclosure and Barring Service CheckThis post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.Certificate of SponsorshipApplications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).UK Registration Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).Employer detailsEmployer nameGreat Ormond Street Hospital for Children NHS Foundation TrustAddressGreat Ormond Street Hospital for Children NHS Foundation TrustGreat Ormond Street HospitalLondonWC1N 3JHUnited KingdomEmployer's websiteEmployer detailsEmployer nameGreat Ormond Street Hospital for Children NHS Foundation TrustAddressGreat Ormond Street Hospital for Children NHS Foundation TrustGreat Ormond Street HospitalLondonWC1N 3JHUnited KingdomEmployer's website