About the role
I'm hiring a Director of Clinical Pharmacology to help power our growing discovery and development portfolio — and to build our clinical pharmacology and pharmacometric capability from the ground up.
All potential candidates should read through the following details of this job with care before making an application.
Sitting within Drug Discovery, you'll be the core quantitative and clinical pharmacology lead across cross-functional project teams, applying MIDD approaches to translate nonclinical PK/PD into human development strategy — informing dose selection, trial design, and risk mitigation across a modality-agnostic pipeline (small molecules, biologics, novel platforms).
You'll:
- Own clinical pharmacology strategy across multiple concurrent programmes, from IND-enabling studies through Phase 1–3
- Lead modelling & simulation — PK/PD, PBPK, population PK/PD, QSP, DDI risk — to drive data-informed decisions
- Partner across Translational xwzovoh Safety, Pharmacology, Biomarkers, DMPK, and Regulatory to embed clinical pharmacology into every development plan
- Author regulatory submissions (IB, IND, NDA/BLA/MAA) and represent us with regulators
- Manage CRO partnerships and bring AI-enabled approaches into the workflow
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