Research Associate in nanoformulation for active transport across the tumour endothelium

About the roleAre you passionate about solving one of the major challenges in drug delivery for cancer therapy using a multidisciplinary nanomedicine approach?We are looking for a highly motivated Postdoctoral Research Associate in Nanomedicine for Cancer to join the Najer Group in the Department of Materials at Imperial College London in collaboration with the Bruna Group at the Institute of Cancer Research (ICR) to tackle a devastating childhood cancer, neuroblastoma.Nanomedicines for cancer struggle to reach their target due to blood vessel barriers hindering access to tumours. In this role you will pioneer a new type of nanomedicine. The nanomedicine is designed to target tumour blood vessels to activate transport across the barrier.What you would be doingYou will be responsible to develop an exciting new type of nanoparticle that is designed to bind to tumour blood vessel cells to activate trans-endothelium transport of the nanomedicine to more efficiently reach tumour cells.The role entails:Formulating nanoparticlesCharacterising the final nanomedicineStudying cell uptake and endothelium transport using a trans-well setupAnalysing data and presenting to colleagues, at workshops and conferencesCollaborating with researchers in both groups and beyondContributing to patient engagement activitiesManaging a CL2 laboratoryWhat we are looking forPhD in Materials Science/Nanomaterials/Biomaterials/Bioengineering/ Microbiology or Cell Biology or a closely related discipline, or equivalent research, industrial or commercial experienceExperience in CL2 mammalian cell culture (essential) and/or CL3 pathogen culture (desirable)Experience in nanoparticle research, including studies in cellsExperience in techniques for cellular analysis (e.g. flow cytometry, confocal imaging)Knowledge in nanomedicine, drug delivery, anticancer therapiesExcellent communication and organisational skillsAbility to work independently and collaboratively within an international research environmentWhat we can offer youJoin a highly multidisciplinary team that performs exciting research in a collaborative fashionContribute to a cutting-edge research project with high translational potentialThe opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanityGrow your career: gain access to Imperial’s sector-leading dedicated career support for researchers as well as opportunities for promotion and progression.As a member of research staff you have 10 development days to use to develop your skills and explore your career prospectsSector-leading salary and remuneration package (including 43 days off a year and generous pension schemes)Be part of a diverse, inclusive and collaborative work culture with various staff networks and resources to support your personal and professional wellbeingFurther informationCandidates who have not yet officially been awarded their PhD will be appointed initially at Research Assistant level (with a salary range of 45,399 to 48,876).For further enquiries, please contact Dr Adrian Najer, queries regarding the application process should be directed to: Darakshan Khan or Claire Isherwood, technical issues, please contact: