Director, Epidemiology & Evidence Strategy

52978Posted: 11/08/2026london, United Kingdom Contract Director, Epidemiology & Evidence StrategyEurope, United States Permanent Permanent | Global Pharmaceutical CompanyOverview We are partnering with a large, global pharmaceutical organisation to appoint a Director, Epidemiology & Evidence Strategy to lead epidemiological input across a confidential portfolio of late-stage assets. This is a senior scientific leadership role, responsible for shaping the epidemiological evidence strategy that underpins regulatory submissions, risk management, and lifecycle planning across multiple indications.Key Responsibilities1. Epidemiological Strategy & LeadershipSet the overarching epidemiology strategy across the portfolio, aligning with regulatory, clinical, and commercial objectives Serve as the senior scientific authority on disease burden, natural history, and background incidence/prevalence for priority indications Represent epidemiology at senior governance forums, advising on programme-level risk and evidence gaps Build and lead a team of epidemiologists, mentoring junior staff and setting scientific standards across studies 2. Study Design & Evidence GenerationDesign and oversee observational studies, including natural history studies, disease registries, and post-authorisation safety/efficacy studies Provide expert methodological oversight on epidemiological approaches, including bias mitigation, confounding control, and causal inference frameworks Lead development of study protocols, statistical analysis plans, and epidemiological sections of regulatory submissions Ensure epidemiological rigor across all evidence-generation activities, from concept through to publication 3. Regulatory & Cross-Functional EngagementAuthor and review epidemiological content for regulatory submissions, risk management plans, and health authority responses Act as the epidemiology lead in interactions with regulatory agencies, responding to scientific queries Partner closely with Biostatistics, Pharmacovigilance, Medical Affairs, and Health Economics to ensure epidemiological evidence is integrated into broader evidence packages Provide epidemiological input into signal detection and benefit-risk assessment activities Impact of the RoleShape the epidemiological evidence foundation for a confidential multi-indication portfolio Strengthen the organisation's scientific credibility with regulators through rigorous epidemiological input Build internal epidemiology capability and governance standards Influence long-term lifecycle and risk management strategy across therapeutic areas Your ProfilePhD in Epidemiology (or closely related discipline) required Extensive experience (12+ years) in epidemiology within pharmaceutical, biotech, or public health settings, including senior/leadership experience Deep expertise in observational study design, causal inference, and pharmacoepidemiological methods Demonstrated experience authoring epidemiological content for regulatory submissions and interacting with health authorities Track record of leading and developing epidemiology teams Strong scientific writing and publication record Excellent stakeholder management skills, with experience presenting to senior governance and regulatory bodies Director, Epidemiology & Evidence Strategy 52731 | Posted: 11/08/2026Europe, United States Permanent Permanent | Global Pharmaceutical CompanyOverview We are partnering with a large, global pharmaceutical organisation to appoint a Director, Epidemiology & Evidence Strategy to lead epidemiological input across a confidential portfolio of late-stage assets. This is a senior scientific leadership role, responsible for shaping the epidemiological evidence strategy that underpins regulatory submissions, risk management, and lifecycle planning across multiple indications.Key Responsibilities1. Epidemiological Strategy & LeadershipSet the overarching epidemiology strategy across the portfolio, aligning with regulatory, clinical, and commercial objectives Serve as the senior scientific authority on disease burden, natural history, and background incidence/prevalence for priority indications Represent epidemiology at senior governance forums, advising on programme-level risk and evidence gaps Build and lead a team of epidemiologists, mentoring junior staff and setting scientific standards across studies 2. Study Design & Evidence GenerationDesign and oversee observational studies, including natural history studies, disease registries, and post-authorisation safety/efficacy studies Provide expert methodological oversight on epidemiological approaches, including bias mitigation, confounding control, and causal inference frameworks Lead development of study protocols, statistical analysis plans, and epidemiological sections of regulatory submissions Ensure epidemiological rigor across all evidence-generation activities, from concept through to publication 3. Regulatory & Cross-Functional EngagementAuthor and review epidemiological content for regulatory submissions, risk management plans, and health authority responses Act as the epidemiology lead in interactions with regulatory agencies, responding to scientific queries Partner closely with Biostatistics, Pharmacovigilance, Medical Affairs, and Health Economics to ensure epidemiological evidence is integrated into broader evidence packages Provide epidemiological input into signal detection and benefit-risk assessment activities Impact of the RoleShape the epidemiological evidence foundation for a confidential multi-indication portfolio Strengthen the organisation's scientific credibility with regulators through rigorous epidemiological input Build internal epidemiology capability and governance standards Influence long-term lifecycle and risk management strategy across therapeutic areas Your ProfilePhD in Epidemiology (or closely related discipline) required Extensive experience (12+ years) in epidemiology within pharmaceutical, biotech, or public health settings, including senior/leadership experience Deep expertise in observational study design, causal inference, and pharmacoepidemiological methods Demonstrated experience authoring epidemiological content for regulatory submissions and interacting with health authorities Track record of leading and developing epidemiology teams Strong scientific writing and publication record Excellent stakeholder management skills, with experience presenting to senior governance and regulatory bodies