Senior Bioinformatics Scientist

Senior Bioinformatics Scientist (Genomic Foundation Models)

All candidates should make sure to read the following job description and information carefully before applying.

London (Hybrid) | Up to £130,000 + Equity | Some flexibility for exceptional candidates

We're partnering with a London-based BioAI company that is doing something genuinely rare.

Backed by one of the world's leading AI infrastructure companies and working alongside frontier AI partners, they've built the largest proprietary biological dataset on the planet, spanning billions of genes across millions of species. Following a recent Series B, they're using that data to train genomic and protein foundation models capable of designing entirely novel biological systems.

Their ambition is to compress decades of biological discovery into years. The dataset they're training on doesn't exist anywhere else, which means the modelling opportunities here are unlike anything available in academia or at other companies working off public data.

The Role

You'll sit at the centre of their foundation model efforts, shaping the data strategy behind their genomic and protein models. You'll be deciding what data the models need, curating and evaluating training datasets, fine-tuning models for real biological applications, and working directly with ML engineers and biologists to translate biological questions into model objectives.

Requirements

• You have built novel deep learning architectures or frameworks applied to genomics or protein modelling. This is the defining requirement for this role. We're looking for people who design and implement models, not solely use or fine-tune existing ones.
• Hands-on experience with Transformer-based or foundation model architectures in a biological context (e.g. Enformer, Nucleotide Transformer, Evo, HyenaDNA, ESM, or comparable)
• Understanding of regulatory genomics, non-coding variant prediction, or gene regulation at a level where you can make modelling decisions informed by the biology
• Experience curating or evaluating training data for large-scale biological models
• Deep learning must be a core competency, not a secondary skill. xwzovoh Strong biology alone is not sufficient, and general ML experience without biological applications won't translate.

Strong Preferences

• Published work applying deep learning to functional genomics or variant effect prediction
• Experience with protein language models (ProGen, ESMFold, or similar)
• Familiarity with models like DeepSEA, Sei, Basenji, BPNet, ChromBPNet, SpliceAI, or AlphaGenome