Senior/Principal Bioinformatician - Transcriptomics

An exciting hybrid working opportunity has arisen for an experienced Bioinformatician to join a high-impact team supporting clinical-stage assets. Working at the interface of biology and data, you’ll play a key role in unlocking insights from complex patient-level omics datasets to better understand disease biology, treatment effects and safety signals. This is a collaborative environment where your work will directly inform critical scientific and clinical decisions. In this role you will: * Analyse and interpret large-scale omics datasets (with a strong focus on bulk and single-cell RNAseq) * Develop and refine bioinformatics pipelines and analytical approaches * Generate meaningful biological insights to support clinical programmes * Work with cross-functional stakeholders to communicate findings clearly and effectively * Ensure robust documentation, reproducibility and best practice coding standards * Contribute to scientific reports, presentations and publications You will bring: * MSc/PhD with significant postdoctoral or industry experience (5+ years) * Deep expertise analysing large bulk and single-cell RNAseq datasets from complex (ideally clinical) studies * Strong programming skills (R essential; others beneficial) and experience in Unix/Linux environments * Confident developing and applying methods for functional interpretation of omics data * Proven ability to build, adapt and understand bioinformatics pipelines, deriving relevant biological insights (not just run them) * A clear, confident communicator, able to translate complex data to a range of shareholders * Ability to document code and follow coding best practices * A detail-oriented, scientifically rigorous mindset If you’re looking for a role where your expertise will genuinely shape scientific understanding and influence decision-making, we’d love to hear from you. Apply now or get in touch for a confidential discussion